The International HIV Dementia Scale: a new rapid screening test for HIV dementia

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dc.creatorSacktora, Ned C.
dc.creatorWong, Matthew
dc.creatorNakasujja, Noeline
dc.creatorSkolasky, Richard L.
dc.creatorSelnes, Ola A.
dc.creatorMusisi, Seggane
dc.creatorRobertson, Kevin
dc.creatorMcArthur, Justin C.
dc.creatorRonald, Allan
dc.creatorKatabira, Elly
dc.date2011-12-15T16:55:05Z
dc.date2011-12-15T16:55:05Z
dc.date2005
dc.date.accessioned2018-09-04T12:32:19Z
dc.date.available2018-09-04T12:32:19Z
dc.descriptionObjective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing this condition. The objective of this study was to evaluate the sensitivity and specificity of a new screening test for HIV dementia, the International HIV Dementia Scale (IHDS) in cohorts from the US and Uganda. Design: Two cross-sectional cohort studies designed to evaluate for the presence of HIV dementia. Methods: Sixty-six HIV-positive individuals in the US and 81 HIV-positive individuals in Uganda received the IHDS and full standardized neurological and neuropsychological assessments. The sensitivity and specificity of varying cut-off scores of the IHDS were evaluated in the two cohorts. Results: In the US cohort, the mean IHDS score for HIV-positive individuals without dementia and with dementia were 10.6 and 9.3 respectively (P < 0.001). Using the cutoff of 10, the sensitivity and specificity for HIV dementia with the IHDS were 80% and 57% respectively in the US cohort, and 80% and 55% respectively in the Uganda cohort. Conclusions: The IHDS may be a useful screening test to identify individuals at risk for HIV dementia in both the industrialized world and the developing world. Full neuropsychological testing should then be performed to confirm a diagnosis of HIV dementia.
dc.identifierSacktora, N. ,Wong, M.,Nakasujja, N., e tal. The International HIV Dementia Scale: a new rapid screening test for HIV dementia Vol 19 No 13
dc.identifier0269-9370
dc.identifier1473-5571
dc.identifierhttp://hdl.handle.net/10570/257
dc.identifier.urihttp://hdl.handle.net/10570/257
dc.languageen
dc.publisherLippincott Williams & Wilkins
dc.subjectHIV
dc.subjectDementia
dc.subjectScreening test
dc.subjectUganda
dc.subjectInternational
dc.subjectScale
dc.titleThe International HIV Dementia Scale: a new rapid screening test for HIV dementia
dc.typeJournal article, peer reviewed
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