Biomarkers of HIV immune reconstitution inflammatory syndrome

Simple item page
dc.creatorBonham, Shuli
dc.creatorMeya, David B
dc.creatorBohjanen, Paul R.
dc.creatorBoulware, David R.
dc.date2011-12-30T18:02:22Z
dc.date2011-12-30T18:02:22Z
dc.date2008
dc.date.accessioned2018-09-04T12:32:16Z
dc.date.available2018-09-04T12:32:16Z
dc.descriptionDysregulation of the immune system drives HIV pathogenesis. As we develop new ways to treat HIV and AIDS, we encounter new clinical ramifications of our treatment on regulatory components of the Immune system. HIV-associated Immune in reconstruction Inflammatory syndrome (IRIS) occurs after initiation of antiretroviral therapy with inappropriate and unbalanced restoration of the immune system, resulting in pathologic Inflammatory reactions with significant morbidity. IRIS is most commonly associated with latent, occur or past infectious, including tuberculosis, Cryptococcus neoformans and Mycobacterium avium complex. We discuss common clinical presentations, new diagnostic modalities, current hypotheses of IRIS pathogenesis and future directions of IRIS-related research, focusing on the identification biomarkers that can be used to predict and diagnose IRIS
dc.identifierBonham, S., Meya, D.B., Bohjanen, P.R., Boulware, D.R. (2008). Biomarkers of HIV immune reconstitution inflammatory syndrome. Biomarkers in Medicine, 2(4)
dc.identifier1752-0363
dc.identifierhttp://dx.doi.org/10.2217/17520363.2.4.349
dc.identifierhttp://hdl.handle.net/10570/277
dc.identifier.urihttp://hdl.handle.net/10570/277
dc.languageen
dc.publisherFuture Medicine
dc.subjectBiomarkers
dc.subjectHAART
dc.subjectIRIS
dc.subjectHIV/AIDS
dc.subjectCytokines
dc.subjectT cells
dc.subjectMycobacterium tuberclosis
dc.titleBiomarkers of HIV immune reconstitution inflammatory syndrome
dc.typeJournal article, peer reviewed
Files
Collections
Dissertation and Thesis