Community-acquired pnemonia in Ugandan adults: short-term parenteral ampicilin therapy for bacterial pnemonia

dc.creatorYoshimine, Hiroyuki
dc.creatorOishi, Kazunori
dc.creatorMubiru, Francis
dc.creatorNalwoga, Hawa
dc.creatorTakahashi, Hidehiko
dc.creatorAmano, Hideaki
dc.creatorOmbasi, Philip
dc.creatorWatanabe, Kiwao
dc.creatorJoloba, Moses
dc.creatorAisu, Thomas
dc.creatorAhmed, Kamruddin
dc.creatorShimada, Masaaki
dc.creatorMugerwa, Roy
dc.creatorNagatake, Tsuyoshi
dc.date2013-07-02T08:17:11Z
dc.date2013-07-02T08:17:11Z
dc.date2001
dc.date.accessioned2018-09-04T12:50:52Z
dc.date.available2018-09-04T12:50:52Z
dc.descriptionA hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short-term parenteral ampicillin followed by oral amoxicillin for these patients in relation to HIV-status. We demonstrated a very high prevalence (75%) of HIV-1 infection. No significant difference was observed with respect to age, gender, prior antibiotic usage, symptoms, laboratory data or bacterial etiology between HIV-1-infected and HIV-uninfected CAP patients. Most strains of Streptococcus pneumoniae (n = 19) and Haemophilus influenzae (n = 8) isolated from HIV-1-infected patients were penicillin-resistant (95%) and β-lactamase producing (75%) strains, respectively. A high percentage of good clinical response was found in both HIV-1-infected (81%) and HIV-uninfected (86%) among 39 patients with CAP due to a defined bacterial pathogen. These data support the use of short-term parenteral ampicillin for patients with bacterial CAP irrespective of HIV-status.
dc.identifierAmerican Journal of Tropical Medicine and Hygiene, 64(3, 4), 2001, pp. 172-177
dc.identifier
dc.identifierhttp://hdl.handle.net/10570/1460
dc.identifier.urihttp://hdl.handle.net/10570/1460
dc.languageen
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.subjectCommunity-Acquired Pneumonia (CAP)
dc.subjectHIV-1
dc.subjectParenteral ampicillin
dc.titleCommunity-acquired pnemonia in Ugandan adults: short-term parenteral ampicilin therapy for bacterial pnemonia
dc.typeOther
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