Community-acquired pnemonia in Ugandan adults: short-term parenteral ampicilin therapy for bacterial pnemonia
dc.creator | Yoshimine, Hiroyuki | |
dc.creator | Oishi, Kazunori | |
dc.creator | Mubiru, Francis | |
dc.creator | Nalwoga, Hawa | |
dc.creator | Takahashi, Hidehiko | |
dc.creator | Amano, Hideaki | |
dc.creator | Ombasi, Philip | |
dc.creator | Watanabe, Kiwao | |
dc.creator | Joloba, Moses | |
dc.creator | Aisu, Thomas | |
dc.creator | Ahmed, Kamruddin | |
dc.creator | Shimada, Masaaki | |
dc.creator | Mugerwa, Roy | |
dc.creator | Nagatake, Tsuyoshi | |
dc.date | 2013-07-02T08:17:11Z | |
dc.date | 2013-07-02T08:17:11Z | |
dc.date | 2001 | |
dc.date.accessioned | 2018-09-04T12:50:52Z | |
dc.date.available | 2018-09-04T12:50:52Z | |
dc.description | A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short-term parenteral ampicillin followed by oral amoxicillin for these patients in relation to HIV-status. We demonstrated a very high prevalence (75%) of HIV-1 infection. No significant difference was observed with respect to age, gender, prior antibiotic usage, symptoms, laboratory data or bacterial etiology between HIV-1-infected and HIV-uninfected CAP patients. Most strains of Streptococcus pneumoniae (n = 19) and Haemophilus influenzae (n = 8) isolated from HIV-1-infected patients were penicillin-resistant (95%) and β-lactamase producing (75%) strains, respectively. A high percentage of good clinical response was found in both HIV-1-infected (81%) and HIV-uninfected (86%) among 39 patients with CAP due to a defined bacterial pathogen. These data support the use of short-term parenteral ampicillin for patients with bacterial CAP irrespective of HIV-status. | |
dc.identifier | American Journal of Tropical Medicine and Hygiene, 64(3, 4), 2001, pp. 172-177 | |
dc.identifier | ||
dc.identifier | http://hdl.handle.net/10570/1460 | |
dc.identifier.uri | http://hdl.handle.net/10570/1460 | |
dc.language | en | |
dc.publisher | American Society of Tropical Medicine and Hygiene | |
dc.subject | Community-Acquired Pneumonia (CAP) | |
dc.subject | HIV-1 | |
dc.subject | Parenteral ampicillin | |
dc.title | Community-acquired pnemonia in Ugandan adults: short-term parenteral ampicilin therapy for bacterial pnemonia | |
dc.type | Other |