Burden of tuberculosis in Kampala, Uganda

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dc.creatorGuwatudde, David
dc.creatorZalwango, Sarah
dc.creatorKamya, Moses R.
dc.creatorDebanne, Sara M.
dc.creatorDiaz, Mireya I.
dc.creatorOkwera, Alphonse
dc.creatorMugerwa, Roy D.
dc.creatorKing, Charles
dc.creatorWhalen, Christopher C.
dc.date2012-09-25T16:03:22Z
dc.date2012-09-25T16:03:22Z
dc.date2008
dc.date.accessioned2018-09-04T12:32:53Z
dc.date.available2018-09-04T12:32:53Z
dc.descriptionObjective: To determine the prevalence and incidence of tuberculosis in one of Uganda’s poor peri-urban areas. Methods: Multi-stage sampling was used to select a sample of households whose members were evaluated for presence of signs and/or symptoms of active tuberculosis; history of tuberculosis treatment; and relevant demographic, socioeconomic, and household environment characteristics. Patients with suspected tuberculosis underwent standardized evaluation for active disease. Findings: A sample of 263 households with 1142 individuals was evaluated. Nineteen people were classified as having had tuberculosis during the one-year reference period (May 2001–April 2002): nine (47%) cases already had been diagnosed through the health care system, while 10 cases (53%) were diagnosed through the survey. The prevalences for all forms of tuberculosis and for sputum smear-positive tuberculosis were 14.0 (95% confidence interval (CI) 7.8–20.3) and 4.4 (CI = 0.83–7.89) per thousand, respectively. The incidences for all forms of tuberculosis and for sputum smear-positive tuberculosis were 9.2 (CI = 3.97–14.4) and 3.7 (CI = 0.39–6.95) per thousand per year, respectively. Conclusion: The rate of tuberculosis in this peri-urban community was exceptionally high and may be underestimated by current surveillance systems. The need for interventions aimed at reducing tuberculosis transmission in this, and other similar communities with high case rates, is urgent.
dc.identifierGuwatudde, D., Zalwango, S., Kamya, M.R., Debanne, S.M., Diaz, M.I., Okwera, A., Mugerwa, R.D., King, C., Whalen, C.C. (2003). Burden of tuberculosis in Kampala, Uganda. Bulletin of the World Health Organization, 81
dc.identifier0042-9686
dc.identifier
dc.identifierhttp://hdl.handle.net/10570/684
dc.identifier.urihttp://hdl.handle.net/10570/684
dc.languageen
dc.publisherWorld Health Organization (WHO)
dc.subjectUganda
dc.subjectTuberculosis
dc.subjectCross-sectional studies
dc.subjectPulmonary tuberclosis
dc.subjectCohort studies
dc.subjectSampling studies
dc.subjectEpidemiology
dc.subjectLung diseases
dc.titleBurden of tuberculosis in Kampala, Uganda
dc.typeOther
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